It's very harmful.
That's why we are supposed to avoid eating certain fish, especially long-lived ones, like a lot of tuna are. They say that Skipjack tuna is better, as it's smaller, and not as long-lived.
And, some people are changing to tested, line-caught tuna by companies like...what is their name?...oh, Safe Catch. They used to test every fish that they catch, and probably still do.
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