My child (w/CF) has been on GSH daily since 9 months old- but the whole family takes it when sick, I took extra when getting my silver fillings removed, when my child o/w CF gets immunized…Dosing is the tricky part. I am a patient of Dr. Guilford and together we talk about what the right dose should be. Comparing experiences I have heard it seems like the CF kids are maybe ¼ to ¾ of a teaspoon (t is 422mg in lipo GSH terms). We started at the suggested dose at the time of ¼ per 30 lbs – but it wasn’t enough for us – we went up and got better results. There is some sense of varying the dose – higher if sick, maybe higher in the winter, try less and see what happens in the summer. Lack of energy might be a sign that I tried something too low…(low for us would be ½ t for several days; in the midst of a bad cold I could give 2 t in a day) We are forging a new path here so it is hard to know what is exactly right – but after years I kind of know what I should be doing for our situation…

There is also the notion of load dosing in the beginning (2 t for an adult) if you are low and then moving to a maintenance dose ( 1 t for an adult)once the body has “refueled” with Parkinson’s and other conditions. I think I saw that with us. I was testing GSH quite a bit and at first I remember increasing GSH and having the results not showing in the blood test – but then at a point the tests seemed to respond to the dosing…Now we have been at our dose for the last 7-10 lbs.; now about 39 lbs. and about ¾ t. + 2 nebs a day of GSH Plus. I did an annual blood test and GSH was in range, and health seems good so I am just staying at 3/4t. as maintenance. At first I just went by the scale – if weight was climbing I felt like I was OK. Interestingly once we had a nagging cough and I panicked and I knew that another CF parent had used 3 t per day (for a few days) to get over an illness so I tried increasing the dose for a couple of weeks. The cough didn’t go away – in hind sight it was prob. allergies – but the weight went way over the trend line. (I was keeping notes and graphing weight then in an attempt to get a grip on things) Isn’t that interesting?

I would love to know if anyone else has thoughts on dosage of lipo vs. caps....

We are giving so many supplements that I try to mix things up – chewables, hiding supps in food. Taking pills, taking liquid – it’s so hard with a child. But it is getting easier. (Wow what a day it was when pills could be swallowed! Changed my life  It might be nice to have the option in the house– caps and liquid so life can be as stress less as possible? (Dr. G feels that Lipo can be taken once per day ) I would think as long as you are getting GSH the form wouldn’t matter – but I ‘m not an expert…And - if you are doing well now , maybe not change anything…