Hi, Carrie! Let me try and address your questions. Our oldest son has always been very compliant with us giving him his regimen. Because of his good attitude, the younger two boys with CF have never complained--they have just followed their older brother's example.

We do one inhaled GSH and several oral doses a day. I think both are very important. When they do have a bad cold (which is very rare), we try to increase the inhalations, and that seems to help.

I cannot think of any negative side effects we have seen. Dr. Clark Bishop is our pulmonologist, and of course he is completely supportive, as is our pediatrician. I think the CF Clinic in Utah is of two minds-which is an improvement! They used to be totally against GSH. Then when the Stanford study of NAC came out in 2005, they became much more open to the idea, but are still insistent on waiting for an FDA-approved product. That's fine for them, but not fine for our family--we love our sons, and we will do everything we can to help them. Even if that means doing something different from current treatment paradigms.

I sincerely believe that the day will come when children newly diagnosed with CF are immediately put on a daily regimen of GSH. And in my opinion, that day cannot come too soon!