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The pufferfish, also known as the blowfish, is the second-most poisonous creature on the planet after the golden poison frog. Nearly all pufferfish contain a toxic substance called tetrodotoxin, which is deadly to humans. According to National Geographic, tetrodotoxin is up to 1,200 times more toxic than cyanide. There is enough poison in one pufferfish to kill 30 adult humans. The poison of a pufferfish, for which there is no antidote, kills by paralyzing the diaphragm, causing suffocation.
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