Steve Kadlecek posted on BV official face book page:

Heads up!

This will cause long delays, heading north, your options to get around it are Hwy146, Hwy3, or Hwy6. I would think Hwy6 would be the least congested

GALVESTON COUNTY: I-45 Gulf Freeway northbound Holland Rd to Deats Rd. crews will switch traffic onto new pavement this weekend requiring alternate lane closures starting Friday, Feb. 14 at 9pm until Feb. 17 at 5am. All entrance ramps and exit ramps between Holland Rd and FM 646 for the northbound lanes will be closed for the weekend as well.