It'll be "there's a new mutation, it all has to start again!" then "you have to get two, no, three jabs now" and then "the jab only lasts for a few months!" and then "you can still spread it even if you had the jab!" and then "we can't open back up as long as there's someone who hasn't had the jab out there...!"
As long as the watchword is "We must be safe above all else!" or "But if it only saves ONE life.." then this is forever. Up to you to end the madness.