"“The benefits and safety of the current vaccine have been evaluated in 19 clinical trials that enrolled more than 27,000 people aged between 15 months and 60 years,” the EMA said. Studies showed Takeda’s vaccine was about 84% effective in preventing people from being hospitalized with dengue and about 61% effective in stopping symptoms four years after getting immunized. "
For the antivax people there is a story about Sanofi Pasteur’s dengue vaccine.
"The green light for the Takeda vaccine comes after Sanofi Pasteur’s dengue vaccine triggered a public health crisis in the Philippines in 2017. The Dengvaxia shot was found to increase the risk of severe disease in people who had not previously been infected with dengue and was linked to the deaths of more than 100 children.
Critics charged that the Sanofi vaccine was rolled out prematurely to about 800,000 children across the Philippines. Numerous scientists and officials were indicted for introducing the vaccine “with undue haste,” that prosecutors said resulted in homicide.
The World Health Organization had previously concluded the Sanofi Pasteur vaccine was safe, but later said children should only be immunized if they were tested first to ensure they had already had dengue".