In February 2018, she (Cumberlege) was appointed by the Health Secretary, Jeremy Hunt, to chair the Independent Medicines and Medical Devices Security Review, investigating reports from women patients about harmful side effects from medicines and medical devices, and how the health service had responded. The Review was reported in July 2020.
It dealt with oral pregnancy test Primodos, anti-epilepsy drug sodium valproate and pelvic mesh repairs. The Review described "a culture of denial, institutional resistance to responding to safety concerns, and an absence of accountability"'