Some good answers (some a bit hasty) which I think reveal it's not so simple. After all masks are supposed to protect healthcare staff from patients' viral emissions. As David says, the amount of viral particles you cop seems to matter. I'll just throw in another angle here to extend this idea; even if the size of the gaps far exceeds the size of particles or droplets (possibly diminishing due to evaporation as in Flash's graphic) they will likely catch a proportion of the droplets; as some presumably hit the mask material. The N25 claims to stop 95% of particles. This is presumably due to the material being mostly 'mask' not 'spaces'. It would also suggest why even a home made mask made of fabric might help; catching even half of the droplets reduces the amount copped by half. This depends on a degree of proportionality in the effect of the substance of concern - wouldn't work if tiny amounts are lethal. Hope helps